Non-tropic hormone

These are the ones that act in the end of the chain reaction on other cells that are not part of other endocrine gland.

This stimulates the anterior pituitary and causes it to release adrenocorticotropic hormone (ACTH; tropic) to the adrenal glands.

Lastly, cortisol (non-tropic) is secreted from the adrenal glands and goes into the bloodstream where it can have more widespread effects on organs and tissues.

Since cortisol is what finally reaches other tissues in the body, it is a non-tropic hormone.

Both tropic and non-tropic hormones are necessary for proper endocrine function.