The North Greenville Trailblazers are the athletic teams representing North Greenville University, located in Tigerville, South Carolina, in intercollegiate sports as a member of the NCAA Division II ranks, primarily competing in the Conference Carolinas (CC; formerly known as the Carolinas–Virginia Athletic Conference (CVAC) until after the 2006–07 school year) since the 2011–12 academic year.

[2] They were also a member of the National Christian College Athletic Association (NCCAA), primarily competing as an independent in the South Region of the Division I level.

The Trailblazers previously competed as a member of the Mid-South Conference (MSC) of the National Association of Intercollegiate Athletics (NAIA) from 1995–96 to 2000–01.

On April 30, 2024, North Greenville announced that they would change their nickname from the Crusaders to the Trailblazers, effective on June 15.

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