[2] The Nossob has its origin in two main tributaries, the Swart-Nossob and Wit-Nossob, meaning black and white respectively.

From this confluence the river course passes the settlements of Leonardville and Aranos to arrive at Union's End, South Africa.

From Union's End the river bed, forming the Botswana border, meanders through the Kgalagadi Transfrontier Park for a distance of over 200 km.

It reaches the southern boundary of the game reserve just north of Twee Rivieren Camp, near its confluence with the Auob River.

However, water is stored underground to provide life for grass and camelthorn trees growing in the river bed.