[1] Nutritional research typically focuses on preventative measure, trying to identify what nutrients or foods will raise or lower risks of diseases and damage to the human body.
[6][7] For example, Prader–Willi syndrome, a disease whose most distinguishing factor is insatiable appetite, has been specifically linked to an epigenetic pattern in which the paternal copy in the chromosomal region is erroneously deleted, and the maternal loci is inactivated by over methylation.
The diet includes relatively high consumption of fruit, vegetables, olive oil, legumes, whole grains and moderate amounts of red wine.
Examples of this include Curcuma longa (turmeric), resveratrol, lycopene, capsaicin, quercetin, and polyphenols in extra virgin olive oil.
It has been suggested that each of these allegedly bioactive compounds, along with several others, interacts with the body's cellular and molecular function, gene expression and epigenome to prevent angiogenesis and the development of neurodegenerative disease.
Examples of genetic related disorders that improve with nutritional correction are obesity, coronary heart disease (CHD), hypertension and diabetes mellitus type 1.
[16] Phenylketonuria, otherwise known as PKU, is an uncommon autosomal recessive metabolic disorder that takes effect postpartum but the debilitating symptoms can be reversed with nutritional intervention.