The most common causes for odontogenic infection to be established are dental caries, deep fillings, failed root canal treatments, periodontal disease, and pericoronitis.
Medical management and treatment of the underlying dental pathology remains a critical initial step in the treatment of odontogenic sinusitis, however recent literature suggests that a significant portion of patients may require endoscopic sinus surgery for successful disease resolution.
A major complicating factor for managing odontogenic infections is the host defence mechanism which can be impaired by systemic illnesses and certain medications.
If treatment is delayed, odontogenic infection can spread into adjacent tissues consequently leading to life-threatening conditions.
Most commonly resulting in respiratory obstruction and sepsis, and less commonly endocarditis, necrotising fasciitis, spondylitis, brain abscess, descending mediastinitis, thoracic empyema, pleuropulmonary suppuration, aspiration pneumonia, pneumothorax, mandibular or cervical osteomyelitis, abscess of the carotid sheath and jugular thrombophlebitis, hematogenous dissemination to distant organs, and coagulation abnormalities.