Offida (Italian: [ofˈfiːda]) is a comune (municipality) in the province of Ascoli Piceno, in the Italian region of Marche, located about 80 km (50 miles) south of Ancona and about 12 km (7 miles) northeast of Ascoli Piceno, on a rocky spur between the valleys of the Tesino (from north) and Tronto (south) rivers.

The true first historical mention dates to 1039, when the Farfa Abbey received the castle of Ophida, being confirmed in 1261 by Pope Urban IV.

In the central apse is a Gothic portal leading to the crypt (with a nave and four aisles—originally only two aisles) which has the same surface of the upper church and is decorated by frescoes attributed to the Master of Offida.

The upper church, with a single hall, has Giottoesque frescoes, some attributed to the Master of Offida (one is dated 1367[4] and others to Giacomo da Campli (16th century).

The grapes are limited to a harvest yield of 10 tonnes per hectare (4 long ton/acre) with the finished wines needing a minimum alcohol level of 12%.