Heading north it winds its way through Sciotoville then intersects with Swauger Valley Rd and Slocum Ave to run very close to the Little Scioto River.

Soon after passing a small neighborhood it joins up with Dixon Mill Rd and runs north until Little Scioto River forces it into a westward curve.

It continues loosely north until Jackson Lake, where it takes a sharp westward turn.

It follows a north-west path until crossing the Carrs Run river and turning north again.

[6][7] In 2003, the Ohio Department of Transportation (ODOT) commenced construction on a $1.8 million project to realign SR 335 from Dixon Mill Road to Gampp Lane in Scioto County east of the CSX railroad line.