The highway travels north through Orrville and east of Rittman, intersecting SR 585 between the two towns.

Just past this intersection, SR 57 meets I-80 (Exit 145) at a double trumpet interchange and continues north, still as a four-lane divided highway, passing the Midway Mall and numerous businesses and hotels before intersecting I-90/SR 2 (Exit 145), less than a mile north of I-80.

SR 57 then runs north toward the east side of Lorain, where it ceases to be a divided highway but remains a four-lane road.

In 2003 the loop from SR 57 southbound to I-90/SR 2 eastbound in this interchange was removed and replaced by a left turn to simplify traffic movements on SR 57, and the opposite loop had been removed by 2004 to make it a six-ramp partial cloverleaf interchange.

[2] This stretch of SR 57 contains a disorganized cluster of roads and exits and has been said to be a high-crash zone, according to city and Ohio Department of Transportation District 3 officials.