Although a route of less than one-quarter mile (0.40 km) in length, SR 578 did pass through two counties: Wood and Lucas.

[3] No sooner than starting from the intersection of SR 65 and Bridge Street in Grand Rapids, SR 578 crossed the Maumee River via a two-lane, four-span steel bridge.

North of the bridge, SR 578 met a pair of driveways (one on either side of the roadway), crossed over a very narrow waterway parallel to the Maumee River, and promptly arrived at its endpoint at the former US 24.

[4] SR 578 was designated in 1937 as a route that was much longer than the short connector that is serves as today.

[5][6][7] In 1942, US 24 was re-routed onto the north side of the Maumee River heading northeast from Napoleon.