Old River (Natchitoches Parish) is a series of interconnected, natural waterways totaling over 25 miles (40 km) in length in Natchitoches Parish, Louisiana.

The river is flanked by Interstate 49 on the west and the Red River of the South on the east, and is one of the many waterways on Isle Brevelle.

[1] St. Anne Chapel at Old River is a historic Catholic chapel founded in the 1800s along the banks of Old River near the community of Cypress.

It is the cultural and religious center of the area's Louisiana Creole people, predominantly of French descent.

This Louisiana state location article is a stub.