Orfani (Greek: Ορφάνι, formerly Ορφάνιον - Orfanion) is a village and a former municipality in the Kavala regional unit, East Macedonia and Thrace, Greece.

[4] The municipal unit of Orfano has a population of 5,076, and the community of Orfani has 774 inhabitants (2021).

In the Ottoman tahrir defter (number 167) of 1530, the settlement is recorded as a village with the name Orfana, within the kaza of Zihne.

[5] The town has been identified with the Byzantine Chrysopolis in Macedonia.

[6][7] This Eastern Macedonia and Thrace location article is a stub.