[2] Orthione griffenis is an Epicaridean isopoda parasite that is found on the gill chamber of Upogebia mud shrimp.

[4] They were likely introduced from cargo ships bound from Asia emptying their ballast tanks off the coast of North America.

[6][7] After being introduced from Asia, Orthione griffenis have established themselves in North America by infesting the mud shrimp Upogebia pugettensis.

This causes a metabolic burdening effect that greatly hampers reproductive ability, which has led to a significant decline in U. pugettensis.

However O. griffenis have been associated with modification of secondary sex characteristics and showed no signs of increasing male mortality.