[2][3] Tilly's work was expectedly met with skepticism, as it warranted a paradigm-shift; however, many labs across the world have been able to reproduce his results over several decades.
[3] In the other, which it calls "OvaTure," it would harvest putative oogonial stem cells from a woman, mature them into oocytes in vitro, and then fertilize them with ICSI.
[6] Dipp, Aldrich, Westphal, and Sinclair had previously worked together to found and develop Sirtris Pharmaceuticals around Sinclair's work on resveratrol — the company was sold to GlaxoSmithKline in 2008 for around $720 million and then was absorbed into GSK in 2013 after reservatrol was abandoned in 2010;[2][3][6] Dipp, Westphal, and Aldrich were also involved in Alnara Pharmaceuticals, which was sold to Eli Lilly in 2010 for around $180 million and was also later abandoned by its purchaser when its technology failed.
[6] The company's A financing round was $6 million, financed by Longwood Fund and Bessemer Venture Partners, and it raised a $37 million B round in early 2012, funded by General Catalyst, BBT Capital Management Advisors, Cycad Group, Hunt BioVentures, RA Capital, Longwood, Bessemer, and other undisclosed investors.
[7] OvaScience held its public offering in 2012, and part of its pitch to investors was that its services would probably not be regulated by the FDA so it would probably be able to start generating significant revenue in the US by the end of 2013, but in 2013 the FDA ruled that it would need to file an investigational new drug application before it could start marketing the service; OvaScience's shares fell 40% in response.