[1] Kayla Harrison, the only two-time Olympic gold medalist in judo in the history of the United States, entered her second PFL playoffs unbeaten in 10 pro bouts.

She faced Genah Fabian who held a 4-1 record and had won both of her PFL regular season bouts against Julija Pajic and Laura Sanchez to advance to the playoffs.

They were set to meet in the 2019 semifinals in October of that year, but Fabian withdrew due to an illness after issues with her weight cut.

[2] The other lightweight semifinal was expected to feature 2019 finalist Larissa Pacheco and former Invicta FC fighter Taylor Guardado.

Top seed Bruno Cappelozza took on Jamelle Jones, who qualified for the playoffs with a knockout of Klidson Abreu after stepping in as an alternate.