2FJU, 2ZKM533018796ENSG00000137841ENSMUSG00000040061Q00722A3KGF7NM_001284297NM_001284298NM_001284299NM_004573NM_001290790NM_177568NP_001271226NP_001271227NP_001271228NP_004564NP_001277719NP_8082361-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 is an enzyme that in humans is encoded by the PLCB2 gene.

[5][6][7] The gene codes for the enzyme phospholipase C β2.

The enzyme catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate.

This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals.

This article on a gene on human chromosome 15 is a stub.