3E7A, 3E7B, 3EGG, 3EGH, 3HVQ, 3N5U, 3V4Y, 4G9J, 4MOV, 4MOY, 4MP0, 4XPN, 1FJM549919045ENSG00000172531ENSMUSG00000040385P62136P62137NM_206873NM_001008709NM_002708NM_031868NP_001008709NP_002699NP_996756NP_114074Serine/threonine-protein phosphatase PP1-alpha catalytic subunit is an enzyme that in humans is encoded by the PPP1CA gene.
PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription.
Studies in both human and mice suggest that PP1 is an important regulator of cardiac function.
Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
[5] Click on genes, proteins and metabolites below to link to respective articles.