556718749ENSG00000142875ENSMUSG00000005034P22694P68181NM_001242862NM_001300915NM_001300916NM_001300917NM_002731NM_182948NM_207578NM_001375560NM_001375561NM_001375562NM_001375563NM_001375564NM_001375565NM_001375569NM_001375571NM_001375572NM_001375573NM_001375574NM_001375575NM_001375576NM_001375577NM_001375578NM_001375579NM_001375580NM_001375581NM_001164198NM_001164199NM_001164200NM_011100NP_001229791NP_001287844NP_001287845NP_001287846NP_002722NP_891993NP_997461NP_001362489NP_001362490NP_001362491NP_001362492NP_001362493NP_001362494NP_001362498NP_001362500NP_001362501NP_001362502NP_001362503NP_001362504NP_001362505NP_001362506NP_001362507NP_001362508NP_001362509NP_001362510NP_002722.1NP_001157670NP_001157671NP_001157672NP_035230cAMP-dependent protein kinase catalytic subunit beta is an enzyme that in humans is encoded by the PRKACB gene.

[5] cAMP is a signaling molecule important for a variety of cellular functions.

The inactive holoenzyme of PKA is a tetramer composed of two regulatory and two catalytic subunits.

cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits.

Three alternatively spliced transcript variants encoding distinct isoforms have been observed.