PRKCD

2YUU, 1YRK558018753ENSG00000163932ENSMUSG00000021948Q05655P28867NM_001354679NM_001354680NM_011103NM_001310682NP_001341608NP_001341609NP_001297611NP_035233Protein kinase C delta type (or PKC-δ) is an enzyme that in humans is encoded by the PRKCD gene.

[6] PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways.

PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters.

Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells.

[7] Protein kinase C delta is also regulated by phosphorylation on various serine/threonine (e.g. T50, T141, S304, T451, T505, S506, T507, S643, S664) and tyrosine residues including Y311 (by SRC).