Pamelia is a town in Jefferson County, New York, United States.

The town was named for Pamelia Williams, wife of landowner and developer General Jacob J.

A small south part of Pamelia was lost when Watertown incorporated in 1869.

New York State Route 37 is a north-south highway east of Interstate 81.

New York State Route 342 is an east-west highway which crosses NY-37 at Pamelia Center.

New York State Route 12 crosses the southwest part of the town.