Paranesti railway station (Greek: Σιδηροδρομικός Σταθμός Παρανεστίου, romanized: Sidirodromikós Stathmós Paranesti) is a railway station that serves the Northern Greek City of Drama, in Drama in East Macedonia and Thrace, Greece.

Opened in June 1895 on what was the Société du Chemin de Fer Ottoman Jonction Salonique-Constantinople JSC, build to connect Thessaloniki and Alexandroupoli.

Following the failed Italian invasion, on 30 April 1941 Bulgaria occupied territory between the Struma River and a line of demarcation running through Alexandroupoli and Svilengrad west of the Maritsa river, occupying the cities of Alexandroupoli (Bulgarian: Дедеагач, romanized: Dedeagach), Komotini (Гюмюрджина, Gyumyurdzhina), Serres (Сяр, Syar), Xanthi (Ксанти), Drama (Драма) and Kavala (Кавала), which it had lost to Greece in 1918.

On 1 January 1971, the station and most of Greek rail infrastructure were transferred to the Hellenic Railways Organisation S.A., a state-owned corporation.

Freight traffic declined sharply when the state-imposed monopoly of OSE for the transport of agricultural products and fertilisers ended in the early 1990s.

In 2009, with the Greek debt crisis unfolding OSE's Management was forced to reduce services across the network.