In the rodent, the parasubiculum is a retrohippocampal isocortical structure, and a major component of the subicular complex.
It receives numerous subcortical and cortical inputs, and sends major projections to the superficial layers of the entorhinal cortex (Amaral & Witter, 1995).
Defined on the basis of cytoarchitecture, it is more similar to the presubiculum than to the entorhinal area (Zilles, 1990), however electrophysiological evidence suggests a similarity with the entorhinal cortex (Funahashi and Stewart, 1997; Glasgow & Chapman, 2007).
To be specific, cells in this area are modulated by local theta rhythm, and display theta-frequency membrane potential oscillations (Glasgow & Chapman, 2007; Taube, 1995).
Furthermore, cells in the parasubiculum, and neighboring presubiculum, fire in relation to the animal's location in space, suggesting properties similar to place cells.