Pareledone is a genus of octopuses in the family Megaleledonidae.

Some octopuses exhibit the ability to alter speeds of sodium and potassium ion movement across cell membranes, allowing them to live in very cold water.

Researchers at the University of Puerto Rico's Institute of Neurobiology found that a member of the Pareledone genus collected from McMurdo Station, Antarctica could speed up the gating kinetics of its potassium channels in cold water to keep up with sodium ion exchange, whose channel is less temperature sensitive.

This alteration in the rate of opening is accomplished through RNA editing, in which specific deamination of an adenosine nucleotide to inosine results in a change in a single amino acid in the potassium channel's voltage sensor, destabilizing the open state.

[4] They are now looking into whether individuals can alter their protein synthesis in response to changing temperatures, or if this change occurs species-wide, over long-term adaptations.