San Roque Parish was founded after the division of Pateros to Pasig by Fray Andres Vehil and Fr.

During the Philippine Revolution, the church was destroyed for the second time during the Battle of Pateros on March 14, 1899.

[3] During World War II, families of the civilians who were arrested, were taken to the church, which served as a prison.

In December 1944, the Japanese soldiers killed many civilians inside the church.

[3] The parish was planned and created by Fray Santos Gomez Marañon and completed on July 1, 1815, to start the construction.