Its principal feast day is on March 19, the Solemnity of St. Joseph, Husband of the Blessed Virgin Mary.

During the 1960s, the Ortigas Company donated 5,030 square metres (54,100 sq ft) of hilly land in what is now Greenhills to the Archdiocese of Manila for the building of a semi-concrete church.

Architect Manuel Mañosa, Jr. visualized the building and Nemesio Montenegro of Taal, Batangas gave it structural form and substance.

In March 1967, it became a parish with an initial 3,500 congregants from the Wack-Wack and White Plains subdivisions and from some areas near Camp Crame.

The laity and the birth of different religious organizations gave significant contribution in the propagation of faith through their evangelization, catechism, charitable projects and other various activities.

The following priests of the Oblates of Saint Joseph comprise the administration of Santuario de San Jose: