Patti is a town and comune in northeastern Sicily, southern Italy, administratively part of the Metropolitan City of Messina, on the western shore of the gulf of the same name.

It is connected to the rest of Sicily by train, via the Patti-San Piero Patti train station, located on the railway line Messina-Palermo, and the A20 Palermo-Messina highway.

It is best known for the remains of its rich monumental Roman Villa and for the impressive ruins of ancient city of Tyndaris nearby.

The town was founded by the Norman king Roger II of Sicily in 1094.

Patti was destroyed by Frederick of Aragon about 1300, on account of its attachment to the House of Anjou; rebuilt in the 16th century, it was later sacked by the Ottoman Turks.