The original high school was located on the current site of Holman Middle School, behind Pattonville's Learning Center at 11055 St Charles Rock Road, but has since moved to behind the Champ Landfill.

[9] All students are required to complete 50 hours of community service in order to receive a diploma.

[citation needed] Students at PHS have the opportunity to participate in the Missouri A+ schools program, allowing 2 years of free tuition at any community college in the state of Missouri if grades and attendance requirements are met.

PHS offers a variety of Honors and AP Classes that give college credit.

Demographics as of 2020:[10] Students at Pattonville High School have the opportunity to participate in activities:[11] Pattonville fields a competitive marching band,[12] and has had success at the national level in jazz band, jazz ensemble, cheerleading, and robotics.