Pederin is a vesicant toxic amide with two tetrahydropyran rings, found in the haemolymph of the beetle genus Paederus, including the Nairobi fly, belonging to the family Staphylinidae.

This is a rash that varies from a slight erythema to severe blistering, depending on the concentration and duration of exposure.

After several steps of Moffatt oxidation, phenylselenation, hydrolysis, and reduction, pederic acid is reached.

This family of compounds is able to inhibit protein and DNA biosynthesis,[8] making it useful to slow the division of cancer cells.

One derivative of pederin, psymberin, has been found to be highly selective in targeting solid tumor cells.