The road passes through the commercial downtown, crossing Norfolk Southern's Buffalo Line and heading into residential areas.

The route heads east-northeast into Limestone Township in Montour County and becomes Broadway, running through more rural areas.

The route crosses the Little Fishing Creek into the borough of Millville and becomes West Main Street, passing residential and commercial areas as it intersects PA 42.

The road heads through open agricultural areas with some woods and residences, reaching the residential community of Rohrsburg.

Here, the route turns sharply north to continue along Rohrsburg Road and passes through more farmland before turning northeast into a mix of farmland and woodland, passing through a corner of Fishing Creek Township before heading into Benton Township.