After Perryville Road, PA 368 enters a small, rural region of Parker Township.

Paralleling Perryville Road to the south, PA 368 passes a more suburban area of Parker Township.

Just after leaving Parkers Landing, Perryville Road, which had been paralleling, merges back into the state route.

After Hagertown Road, PA 368 progresses straight to the northeast through a rural, undeveloped terrain.

[2] At the Myers Hollow Road intersection, PA 368 turns off its eastern progression and onto a northeastern one.

Changing official names from Route 368 to Main Street, the highway enters the downtown area.