Persico Dosimo (Cremunés: Pérsec Dóseem) is a comune (municipality) in the Province of Cremona in the Italian region Lombardy, located about 80 kilometres (50 mi) southeast of Milan and about 8 kilometres (5 mi) northeast of Cremona.

Persico Dosimo borders the following municipalities: Castelverde, Corte de' Frati, Cremona, Gadesco-Pieve Delmona, Grontardo, Pozzaglio ed Uniti.

Among the local churches are:

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