The Piquirí River rises in the south of Mato Grosso at the convergence of the Peixe de Couro and the Itiquira rivers.

It continues to meander west along the border between Mato Grosso and Mato Grosso do Sul, receiving the Braço de São Lourenço River from the right (north).

[1] It defines the southern boundary of the Encontro das Águas State Park, joining the São Lourenço at the southwest boundary of the park.

[2] The region, rich in watercourses, supports diverse pantanal vegetation.

This article related to a river in Mato Grosso, Brazil is a stub.