Pregnanetriol, or 5β-pregnane-3α,17α,20α-triol, is a steroid and inactive metabolite of progesterone.

Urine excretion of pregnanetriol can be measured over a period of 24 hours.

Elevated urine pregnanetriol levels suggest adrenogenital syndrome.

In monitoring treatment with cortisol replacement, elevated urine pregnanetriol levels indicate insufficient dosage of cortisol.

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