These altered humans were set up as sleeper agents, unaware of their natures until a signal from the Operation: Zero Tolerance base activated their programming.
On board scanning and homing sensors which enable them to detect the presence of Homo Superior within their vicinity, backed by combat computers which allow them to compensate for surprising events (such as the arrival of police cars) faster than normal humans.
Finally, their programming may use the natural personality along with the original form of the host to lull unsuspecting targets into conversation, at which point they dampen their powers and kill them.
Other tools Karima shows that Omega Sentinels are equipped with include adaptive countermeasure facilities which enable them to fabricate specialized weaponry tailored to counter specific mutant adversaries.
[1] Able to become resilient towards damage dealt prior to their chassis, as well as produce weaponized solutions angled towards dealing with a specific mutant target.