4RUH5574866054ENSG00000133313ENSMUSG00000024644Q96KP4Q9D1A2NM_001370254NM_001289531NM_023149NP_001357183NP_001276460NP_075638Cytosolic non-specific dipeptidase (EC 3.4.13.18) also known as carnosine dipeptidase 2 is an enzyme that in humans is encoded by the CNDP2 gene.

[5][6][7] This enzyme catalyses the hydrolysis of dipeptides, preferentially those containing hydrophobic amino acids.

The human enzyme uses manganese ions as a cofactor.

[8] In addition to its function as a peptidase, the enzyme also functions to generate N-lactoyl amino acids, such as N-lactoyl-phenylalanine, via the process of "reverse proteolysis".

[9] A similar pathway conjugates amino acids to Beta-hydroxybutyric acid.