Proton ATPase

Here it serves as a functional equivalent to the Na+/K+ ATPase of animal cells; i.e. it energizes the plasma membrane by forming an electrochemical gradient of protons (Na+ in animal cells), that in turn drives secondary active transport processes across the membrane.

This pump is found in the plasma membrane of cells in the gastric mucosa and functions to acidify the stomach.

V-type ATPases acidify the lumen of the vacuole (hence the symbol 'V') of fungi and plants, and that of the lysosome in animal cells.

[10] The reaction cycle involves tight binding of ATP but proceeds without formation of a covalent phosphorylated intermediate.

The reaction cycle involves tight binding of ATP but proceeds without formation of a covalent phosphorylated intermediate.