Pulau Ayau, often called Pulau Aju or simply Ajoe, is a small Indonesian island located in the Ayau Islands above the northern tip of the Waigeo Islands.

Pulau Ayau is administratively part of the Raja Ampat Regency in the Southwest Papua Province of Indonesia.

The two major settlements on the island include Imbik Kuan and Ayu.

Pulau Ayau and all the islands in the Ayau Archipelago were occupied by the Japanese Empire during World War II from 1942 until the end of the war in 1945.

This Southwest Papua location article is a stub.