RDNA (Radeon DNA[2][3]) is a graphics processing unit (GPU) microarchitecture and accompanying instruction set architecture developed by AMD.

The first product lineup featuring RDNA was the Radeon RX 5000 series of video cards, launched on July 7, 2019.

[11] The third iteration of RDNA was announced on November 3, 2022, and is featured in the Radeon RX 7000 series of consumer desktop and mobile graphics cards.

[12] The fourth iteration of RDNA was unveiled on January 6, 2025 at CES[13] and is used in the Radeon RX 9070 series of desktop graphics cards.

[18] The architecture features a new processor design, although the first details released at AMD's Computex keynote hints at aspects from the previous Graphics Core Next (GCN) architecture being present for backwards compatibility purposes, which is especially important for its use (in the form of RDNA 2) in the major ninth generation game consoles (the Xbox Series X/S and PlayStation 5) to preserve native compatibility with their pre-existing eighth generation game libraries designed for GCN.

[5]: 2 [19] AMD's GPUOpen website hosts a PDF document aiming to describe the environment, the organization and the program state of RDNA devices.

It details the instruction set and the microcode formats native to this family of processors that are accessible to programmers and compilers.

[27] Additional features confirmed by AMD include real-time, hardware accelerated ray tracing, "Infinity Cache", mesh shaders, sampler feedback and variable rate shading.

[27] AMD unveiled the Radeon RX 6000 series, its next-gen RDNA 2 graphics cards at an online event on October 28, 2020.

[40][41] An RDNA 2 integrated GPU with 2 compute units is included in the I/O die on AMD's Zen 4-based Ryzen 7000 Series CPUs.