It is operated and supervised by the Department of Education, with a curriculum heavily focused on math and science.
Students who belong to the upper 10% of the Grade VI graduating class and who have been recommended by their respective principals are qualified to take the entrance examination.
The schools offer an accelerated curriculum for math, science and information and communications technology and a custom-made curriculum tailored for the school in the areas of the English and Filipino language, social studies, and humanities, with required courses and a wide selection of electives.
Students have an opportunity to do independent research, and many compete in the annual Intel Science Fair.
Seniors have human biology, analytical chemistry and electricity, electronics, electromagnetics, and vectors.
Linear algebra, analytic geometry, plane and spherical trigonometry, and statistics in research were taken during sophomore.
Grammar and composition is tackled by freshmen and sophomores, while journalism, and speech and drama are included in the junior and senior course respectively.
Juniors tackle pagbasa at pagsulat sa iba't ibang disciplina (reading and writing in different disciplines) while seniors learn about retorika (rhetoric).
Included in their panatikan (literature) course are Ibong Adarna, Florante at Laura, Noli Me Tangere, and El Filibusterismo, which are tackled during freshman, sophomore, junior, and senior years, respectively.
Sociology, geography, economics, and political science are learned during freshman, sophomore, junior and senior, respectively.
The annual subsidy of RSHSs is divided as follows: 10% for the procurement of supplies and materials for mathematics, science and English, 15% procurement of instructional materials including textbooks for Science, Mathematics, English, and other subject areas, professional books, video materials and software in science, mathematics and English including internet subscription, 20% for procurement of science and mathematics equipment including the maintenance and repair of previously owned equipment and upgrading computers and printers, 12.5% will go for payment of electric and water bills, 25% for expenses for training/professional upgrading of all teachers, principals/OICs directly managing RSHSs, including attendance in seminars that may be sponsored by DepEd or other agencies; expenses for students participation in science and mathematics related activities, 12.5% for student researches and projects, and 5% for extra essential services such as security services.
Students of RSHS receive a monthly stipend from the local government of its respective region.
This monthly stipend is intended to support the academic expenses of the students such as research projects.
The test subjects administered in BNHS-RSHS annex MIMAROPA were, Geometry, Technical Writing, Botany and Business Mathematics.
The Congress aimed to provide effective medium for the promotion of science culture among RSHS students, formulate strategies to sustain quality delivery of science and mathematics education, encourage research and development and create pockets of excellence among RSHSs.
The 2006 second RSHS Congress was hosted and held at CARAGA Regional Science High School.