Oberleutnant zur See Reinhold Saltzwedel (23 November 1889 – 2 December 1917) was a successful and highly decorated German U-boat commander in the Kaiserliche Marine during World War I.

He sank a total of 111 merchant vessels for 172,824 gross register tons (GRT).

Reinhold Saltzwedel was born on 23 November 1889 in Rosenberg, Upper Silesia.

Saltzwedel was a Leutnant zur See when World War I broke out and Adjutant on the SMS Kaiser.

On 18 September 1917, he became the commanding officer of UB-81, aboard which he died on 2 December after UB-81 ran into a mine.