The 1st Virginia Infantry Regiment was an infantry regiment raised in the Commonwealth of Virginia for service in the Confederate States Army during the American Civil War.

Its first colonel, Patrick T. Moore, was severely wounded on July 18, 1861, in the skirmish at Blackburn's Ford, and Lt. Col. W.H.

The companies (with original commanders) were: It fought at the Battle of First Bull Run (First Manassas) in a brigade under James Longstreet and in August totaled 570 men.

Later the unit was involved in the capture of Plymouth, the conflicts at Drewry's Bluff and Cold Harbor, the Siege of Petersburg south and north of the James River, and the Appomattox Campaign.

This regiment lost twenty-two percent of the 140 engaged at the Battle of Second Bull Run (Second Manassas), had 9 wounded at the Battle of Fredericksburg, and had more than half of the 209 at Gettysburg disabled.