Rocaglamide is a natural product which belongs to a class of molecules called flavaglines.

[1][2] This compound was isolated in 1982 by Ming-Lu King (金明儒) and colleagues based on its antileukemic activity.

Roc- means Republic of China (中華民國), where this product was first isolated; aglamide indicates this product is isolated from Large-leaved Aglaia (Scientific name: Aglaia rimosa[4]).

Like other flavaglines, rocaglamide displays potent insecticidal, antifungal, anti-inflammatory and anticancer activities.

[6] Although other syntheses have been described since, Trost’s remains the only one to afford rocaglamide in an enantio-specific manner.