Rochelle is an unincorporated community in Alachua County, Florida, United States.

Rochelle was at a junction on the Florida Southern Railway (later, the Plant System), with lines running to Gainesville, Ocala and Palatka.

In 1884, the community name was changed again, to Rochelle, the maiden name of Governor Perry's wife.

The Great Freeze of 1894–1895 destroyed the citrus industry in the area, and the town declined afterwards.

[6] Today, the only remnants of the former town are now the schoolhouse, the General Pacific plant, a radio tower, and some houses and barns.