Micanopy (/ˌmɪkəˈnoʊpi/ ⓘ MIK-ə-NOH-pee) is a town in Alachua County, Florida, United States, located south of Gainesville.

This municipality contains a number of antique stores, as well as several restaurants, a library, firehouse, and post office.

A historical marker in the area notes that Spanish explorer Hernando de Soto recorded finding a village of the Timucua portion of the Potano tribe located near by in 1539.

[6] In 1774, the American naturalist William Bartram recorded his impressions of a proto-Seminole village named "Cuscowilla".

One of the early settlers of the area was Moses Elias Levy, a wealthy Jewish businessman and philanthropist who was involved in West Indies shipping and other interests.

[1] Chief Micanopy lived about 60 miles (97 km) south in present-day Sumter County.

The historian C. S. Monaco has suggested that the town was named after Micanopy "to appease the chief and acknowledge his original authority over the land.

In 1895, a rail line was laid from Micanopy by the Gainesville and Gulf Railroad, and by 1889, reached to Irvine and Fairfield in Marion County, and Sampson City in Bradford County, where it connected to the Atlantic, Suwannee River and Gulf Railway and the Georgia Southern and Florida Railroad.

The climate in this area is characterized by hot, humid summers and generally mild winters.

Micanopy hosts an annual autumn art festival, in which both local and non-local artists participate.

Micanopy Historical Society Museum, housed downtown in the Thrasher Warehouse, features displays of local and town history that range from the early Native Americans, to naturalist William Bartram’s travels in the region, to the Seminole Wars and the Civil War.

[7] Paynes Prairie Preserve State Park is a major source of outdoor recreation for the town and the county as a whole.

[20] Micanopy is mentioned in the Tom Petty song "A Mind with a Heart of Its Own" from the album Full Moon Fever.