The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus.
Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.
The full-length nature of all transcript variants has not been determined.
[7] This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis.
This article on a gene on human chromosome 1 is a stub.