Neuroserpin

[5] It is associated with Familial encephalopathy with neuroserpin inclusion bodies.

Serine protease inhibitors of the serpin superfamily are involved in many cellular processes.

Neuroserpin was first identified as a protein secreted from the axons of dorsal root ganglion neurons (Stoeckli et al., 1989).

It is expressed in the late stages of neurogenesis during the process of synapse formation.

[supplied by OMIM][5] SERPINI1 has been shown to interact with Tissue plasminogen activator.