2VDX, 2VDY, 4BB2, 4C41, 4C4986612401ENSG00000277405ENSG00000170099ENSMUSG00000060807P08185Q06770NM_001756NM_007618NP_001747NP_031644Transcortin, also known as corticosteroid-binding globulin (CBG) or serpin A6, is a protein produced in the liver in animals.
This is the major transport protein for glucocorticoids and progestins in the blood of most vertebrates.
The gene localizes to a chromosomal region containing several closely related serine protease inhibitors (serpins).
[11] A similarly small fraction of serum estradiol is bound to transcortin as well.
[citation needed] Transcortin is produced by the liver and is increased by estrogens.