Saint-Pierre-de-Vassols (French pronunciation: [sɛ̃ pjɛʁ də vasɔl]; Provençal: Sant Pèire de Vassòus) is a commune in the Vaucluse département in the Provence-Alpes-Côte d'Azur region of southeastern France.

It is the birthplace of Blaise Francois Pagan (1603-1665), a French soldier and military engineer.

His work, Les Fortifications, was the dominant text of its era on military fortifications and a significant influence on Sébastien Le Prestre de Vauban.

[3] The village is located near Mont Ventoux, often used as a stage on the Tour de France.

It is one of the toughest climbs in professional cycling, and British cyclist Tom Simpson died here in 1967.