[2] Other high grade carcinomas can mimic SDC.

[4] Therapeutically relevant genetic alterations include ERBB2/Her2 amplification, PIK3CA and/or HRAS mutations.

[5][6] The typical presentation is a rapidly growing mass with associated pain.

[2] This may be seen in association with neck lymph node swelling (cervical lymphadenopathy), due to metastases, and facial nerve paralysis.

Their histologic appearance is similar to ductal breast carcinoma.