Epithelial-myoepithelial carcinoma

Epithelial-myoepithelial carcinoma (EMCa) is a rare malignant tumour that typically arises in a salivary gland and consists of both an epithelial and myoepithelial component.

[2] EMCas are diagnosed by examination of tissue, e.g. a biopsy.

This tumour is characterised by biphasic tubular structures composed of inner ductal and outer clear myoepithelial cells.

Its appearance is very similar to adenomyoepithelioma of the breast, which may be the same tumour at a different anatomical site.

[3] The histologic differential diagnosis includes adenoid cystic carcinoma and pleomorphic adenoma.