San Emigdio Creek, formerly Arroyo de San Emigdio (Spanish for Saint Emygdius Creek), is a 33 kilometres (21 mi)[2] northward-flowing stream in western Kern County, central California.

The San Emigdio Creek headwaters are on the northeast slope of Mount Pinos, 2 miles (3.2 km) south of Tecuya Ridge in the San Emigdio Mountains.

In years of heavy rainfall it would be a tributary to the Connecting Slough, the slough between Kern Lake and Buena Vista Lake which has been dry for decades due to agricultural diversion, pumping, and a lowering groundwater table.

Its mouth provided a watering place between Cuddy Valley in the south and Arroyo de Amargosa (Bitterwater Creek) to the northwest near Buena Vista Lake.

The place where the creek emerged from the foothills of the San Emigdio Mountains was the location of Mexican land grant Rancho San Emidio of Alta California, granted in 1842 to José Antonio Dominguez.